Dr Andrew Osborne

Article

• Levray, Y.S. and Bana, Bianca and Tarr, S.J. and McLaughlin, E.J. and Rossi-Smith, P. and Waltho, A. and Charlton, G.H. and Zenezini Chiozzi, R. and Straton, C.R. and Thalassinos, Kostas and Osborne, Andrew (2023) Formation of ER-lumenal intermediates during export of Plasmodium proteins containing transmembrane-like hydrophobic sequences. PLoS Pathogens ISSN 1553-7374.
• Osborne, Andrew (2020) Use of split-dihydrofolate reductase for the detection of protein-protein interactions and simultaneous selection of multiple plasmids in Plasmodium falciparum. Molecular and Biochemical Parasitology 238, pp. 111292. ISSN 0166-6851.
• Davies, H. and Nofal, S. and Mclaughlin, E. and Osborne, Andrew (2017) Repetitive sequences in malaria parasite proteins. FEMS Microbiology Reviews 41 (6), pp. 923-940. ISSN 1574-6976.
• Osborne, Andrew and Thalassinos, Konstantinos and Davies, Heledd (2016) Expansion of Lysine-rich repeats in Plasmodium proteins generates novel localisation sequences that target the periphery of the host Erythrocyte. Journal of Biological Chemistry 291, pp. 26188-26207. ISSN 0021-9258.
• Tarr, Sarah J. and Osborne, Andrew R. (2015) Experimental determination of the membrane topology of the Plasmodium Protease Plasmepsin V. PLoS One 10 (4), pp. e0121786. ISSN 1932-6203.
• Tarr, Sarah J. and Moon, R.W. and Hardege, Iris and Osborne, Andrew R. (2014) A conserved domain targets exported PHISTb family proteins to the periphery of Plasmodium infected erythrocytes. Molecular and Biochemical Parasitology 196 (1), pp. 29-40. ISSN 0166-6851.
• Tarr, Sarah J. and Cryar, Adam and Thalassinos, Konstantinos and Haldar, K. and Osborne, Andrew R. (2013) The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell. Molecular Microbiology 87 (4), pp. 835-850. ISSN 0950-382X.
• Osborne, Andrew R. and Speicher, K.D. and Tamez, P.A. and Bhattacharjee, S. and Speicher, D.W. and Haldar, K. (2010) The host targeting motif in exported Plasmodium proteins is cleaved in the parasite endoplasmic reticulum. Molecular and Biochemical Parasitology 171 (1), pp. 25-31. ISSN 0166-6851.
• Erlandson, K.J. and Miller, S.B.M. and Nam, Y. and Osborne, Andrew R. and Zimmer, J. and Rapoport, T.A. (2008) A role for the two-helix finger of the SecA ATPase in protein translocation. Nature 455 (7215), pp. 984-987. ISSN 0028-0836.
• Erlandson, K.J. and Or, E. and Osborne, Andrew R. and Rapoport, T.A. (2008) Analysis of Polypeptide movement in the SecY channel during SecA-mediated protein translocation. Journal of Biological Chemistry 283 (23), pp. 15709-15715. ISSN 0021-9258.